Vasculitis

Systemic vasculitis and immune-mediated renal diseases require structured and highly reliable serological testing. Inflammatory vascular damage and glomerular involvement may progress rapidly and demand precise antibody assessment.

Our portfolio covers the full spectrum of ANCA and anti-GBM diagnostics. We combine classical immunofluorescence assays on ethanol- and formalin-fixed neutrophils with advanced IFA-plus formats, dual slides, and fully automated AKLIDES® systems.

CytoBead® technology integrates pattern recognition and antigen-specific differentiation including PR3, MPO, GBM, and dsDNA — within a single streamlined workflow.

Qualitative dot and line immunoassays, as well as quantitative PR3 and MPO assays, further expand diagnostic capabilities and support both screening and disease monitoring.

Our solutions deliver standardized, sensitive, and clinically meaningful results from ANCA pattern detection to precise antigen identification in ANCA-associated vasculitis, RPGN, and Goodpasture syndrome.

4028 – ANCA Dot
Highlights Qualitative dot immunoassay for IgG antibodies against MPO, PR3, and GBM Uses highly purified native (MPO, PR3) and recombinant (GBM) human antigens Supports diagnosis of ANCA-associated vasculitis and autoimmune...
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4058 – Anti-MPO
Highlights Use of IgG antibodies against myeloperoxidase (MPO) Ready-to-use (exception: wash buffer), color- and barcoded reagents Quality assured handling in routine laboratories Short incubation times (60 min / 30 min...
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4060 – AKLIDES® cANCA
Highlights Slides coated with ethanol-fixed human granulocytes Qualitative determination of IgG antibodies against neutrophil cytoplasmic antigens (ANCA) Screening test to support the diagnosis of systemic vasculitis (SV) Ready-to-use reagents (except...
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4072 – AKLIDES® pANCA
Highlights Slides coated with formalin-fixed human granulocytes Screening test to support the diagnosis of systemic vasculitis (SV) Ready-to-use reagents (exception: wash buffer) Qualitative determination of IgG antibodies against neutrophil cytoplasmic...
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4123 – AKLIDES® Anti-GBM
Highlights Use of purified rabbit IgG as solid-phase antigen Monkey kidney tissue sections as substrate for reliable visualization of antibody binding Supports diagnosis of autoimmune glomerulonephritides, including Goodpasture syndrome Facilitates...
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4259 – Anti-PR3 hs
Highlights Use of IgG antibodies against proteinase 3 (PR3) Ready-to-use (exception: wash buffer), color- and barcoded reagents Quality assured handling in routine laboratories Short incubation times (60 min / 30...
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4270 – AKLIDES® CytoBead® ANCA
Highlights Slides coated with cryostat tissue sections of human ethanol-fixed granulocytes and beads coated with PR3, MPO, and GBM Semi-quantitative determination of IgG antibodies against ANCA Ready-to-use reagents (exception: PBS...
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4472 – AKLIDES® ANCA dual
Highlights Slides coated with ethanol and formalin fixed human granulocytes Specific detection of IgG antibodies against neutrophil cytoplasmatic antigens (ANCA) Support for the diagnosis of systemic vasculitis Qualitative and semi-quantitative...
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5018 – DotDiver ANCA
Highlights Use of IgG antibodies against MPO, PR3, and GBM Qualitative line immunoassay for the determination of IgG antibodies in human serum Supports the diagnosis of chronic atrophic gastritis (type...
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8063 – CytoBead® ANCA
Highlights IFA for IgG antibodies in serum Detects ANCA and GBM antibodies Supports vasculitis, autoimmune renal disorders, and Goodpasture syndrome diagnosis Uses antigen-coated beads and tissue sections FITC-labeled secondary antibodies...
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