6119 – Calprotectin Rapid

The Calprotectin Rapid is a qualitative immunoassay for the determination of Calprotectin in human stool samples. The Calprotectin Rapid intended as an aid in the diagnosis of inflammatory bowel disease in conjunction with other clinical and laboratory findings

Inflammatory bowel disease (IBD) is diagnosed via the detection of faecal calprotectin. Calprotectin, mainly located in cytoplasmic neutrophil granulocytes, plays a major role in immune response following its releases after activation of neutrophils. The released calprotectin act as markers of inflammation evident by their presence in the serum, body fluids and faeces; thus acting as alternative marker of neutrophil entry into the intestinal lumen: In this way, organically induced intestinal diseases can be effectively differentiated from functional intestinal disorders like irritable bowel syndrome.

Rapid immunochromatographic assays are widely used for the determination of specific antigens. If antigens are present in the patient´s sample, they are recognized by to color-coded antigen-specific antibodies. The generated immune complex migrates through the test strips by capillarity. The test strips are coated with additional antigen-specific antibodies. If antigens are present in the patient´s sample, the formed immune complex bind to the antibodies and colored bands become visible on the test strip. The signal intensity of the reaction product is proportional to the antigen concentration in the sample.

The immunoassay is designed for manual professional in vitro diagnostic use.

Product summary

Title Calprotectin Rapid
Product code 6119
Indication Inflammatory bowel disease
Description Rapid immunochromatographic test for the determination of calprotectin in human stool samples
Format Test strips coated with monoclonal antibodies against calprotectin
Incubation time 10 min.
Sample volume 1-2 g/mL stool sample
No. of determinations 10 (10 x 1) determinations

Restricted downloads - Password required