5066 – DotDiver ANAcyto 10
The DotDiver ANAcyto 10 is a qualitative dot immunoassay for the determination of IgG antibodies against nuclear and cytoplasmic antigens (Jo-1, PL-7, PL-12, EJ, OJ, KS, ZO, HA, SRP and P0) in human serum. The DotDiver ANAcyto 10 is intended as an aid in the diagnosis of autoimmune myositis diseases in conjunction with other clinical and laboratory findings. The immunoassay is designed for semi-automated use with the DotDiver instrument. The immunoassay is designed for professional in vitro diagnostic use.
Polymyositis, an idiopathic inflammatory muscle disorder with unclear etiology, is characterized by muscle weakness, atrophy of peripheral muscles, biochemical and electromyographic signs of muscle damage, with skin alterations. Autoantibodies to t-RNA synthetases are found in a large group of myositis patients. Specific autoantigens in polymyositis include histidyl (Jo-1), threonyl (PL-7), alanyl (PL-12), glycyl (EJ), isoleucyl (OJ), asparaginyl (KS), tyrosyl (HA), and phenylalanyl (ZO) synthetases.
|Title||DotDiver ANAcyto 10|
|Indication||Autoimmune myositis diseases|
|Description||Dot immunoassay for the qualitative determination of IgG antibodies against nuclear and cytoplasmic antigens in human serum|
|Format||Test strips coated with Jo-1, PL-7, PL-12, EJ, OJ, KS, ZO, HA, SRP and P0|
|Total incubation time||64 min.|
|Sample volume||10 µL serum|
|No. of determinations||24 x 10|