2042 – SELco® TRAb human 1 step

MEDIPAN SELco® TRAb human is a competitive radio-receptor assay used for the quantitative determination of Thyrotropin (TSH) receptor autoantibodies in human serum.

Thyrotropin (TSH) receptor autoantibodies (TRAb), a hallmark of Graves’ disease, provides an effective means for the disease’ diagnosis: these autoantibodies mimic effects of TSH on the thyroid cell leading to increased blood levels of thyroid hormones thyroxine (T4) and triiodothyronine (T3). Detection and quantification of these antibodies provide a valuable means for the differential diagnosis of hyperthyroidism and control of Graves’ disease. This differential diagnosis may be applied pre- and post- treatment by anti-thyroid drugs, 131-radioiodine or surgery.

Depending on the TRAb concentration, pregnant women with Grave’s disease stand the risk of transferring their autoantibodies to the foetus via the placental; the higher the mother’s TRAb concentration, the greater the risk of transfer to the foetus and subsequent development of Grave’s diseases in the uterus, leading to congenital hyperthyroidism.

Product summary

Title SELco® TRAb human 1 step
Product code 2042
Indication Thyroid disease
Description Radioimmunoassay for the quantitative determination of antibodies against TSH receptor (TRAb) in human serum
Format Coated tube technology
Total incubation time 120 min.
Sample volume 100 µL
No. of determinations 100 (93 x 1) + 5 x Calibrators + 2 x Controls

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