4067 – Anti-Faktor H
Intended Purpose
The Anti-Faktor H is a quantitative immunoassay for the determination of IgG antibodies against complement factor H (CFH) in human serum. The Anti-Faktor H is intended as an aid in the diagnosis of atypical hemolytic-uremic syndrome (HUS) in conjunction with other clinical and laboratory findings. The immunoassay is designed for manual professional in vitro diagnostic use.
Diagnostic Relevance
HUS is a disease of small blood vessels, characterized by hemolytic anemia, thrombocytopenia and acute renal failure, with toxin forming Escherichia coli bacteria (Shiga toxin, Vero toxin) being the most common cause is an infection with. This condition is due to disorder of complement regulation, a genetic mutations or antibodies to complement factor H.
Product Specifications
| Title | Anti-Faktor H |
| Product code | 4067 |
| Indication | Hemolytic-uremic syndrome (HUS) |
| Description | Enzyme immunoassay for the quantitative determination of IgG antibodies against complement factor H in human serum |
| Format | Microtiter plate coated with recombinant human factor H |
| Total incubation time | 105 min. |
| Sample volume | 10 µL serum |
| No. of determinations | 48 (41 x 1) + 5 x Calibrators + 2 x Controls |