1652 – SELco® FT3
The SELco® FT3 is a quantitative immunoassay for the determination of free Triiodothyronine (FT3) in human serum. The SELco® FT3 is intended as an aid in the diagnosis of thyroid diseases in conjunction with other clinical and laboratory findings. The immunoassay is designed for manual professional in vitro diagnostic use.
The SELco® FT3 is a quantitative immunoassay for the determination of free Triiodothyronine (FT3) in human serum. The SELco® FT3 is intended as an aid in the diagnosis of thyroid diseases in conjunction with other clinical and laboratory findings.
The circulation of thyroid hormones (thyroxine, T4 and triiodothyronine, T3) is distributed into two compartments; a major protein bound one, and a minor free fraction. Alterations in the total thyroid hormone in blood may be due to changes of binding protein concentrations, or synthesis of thyroid hormone. Thyroid disorders then exist due to persistent change of free unbound fractions. This indication serves as clinical hint, in that total T4 and T3 is dependent on the knowledge of functional levels of binding proteins, measured at length. Thyroid gland triiodothyronine T3 is regarded as the most biologically active among the thyroid hormones produced in the thyroid gland; up to 80 % via de-iodination of T4 in peripheral tissues. Increase in free T3 (FT3) is generally associated with hyperthyroidism. In many cases, a single increased FT3 indicates a T3-thyrotoxicosis; hence as diagnostic tool, in the follow-up of patients who are subject to a therapy with triiodothyronine, the FT3 measurement is also necessary.
|Description||Radioimmunoassay for the quantitative determination of free Triiodothyronine (FT3) in human serum|
|Format||Coated tube technology|
|Total incubation time||60 min|
|Sample volume||100 µL|
|No. of determinations||100 (92 x 1) + 6 x Calibrators + 2 x Controls|