1450 – SELco® TSH rapid
The SELco® TSH rapid is a quantitative immunoassay for the determination of thyrotropin (TSH) in human serum. The SELco® TSH rapid is intended as an aid in the diagnosis of thyroid diseases in conjunction with other clinical and laboratory findings. The immunoassay is designed for manual professional in vitro diagnostic use.
The biosynthesis of Tg is regulated by thyroid-stimulating hormone (TSH), also known as thyrotropin, a pituitary hormone that stimulates the thyroid gland to produce thyroid hormones thyroxine (T4), and then triiodothyronine (T3). T4 and T3 regulate the secretion of TSH by a negative feedback mechanism; T3 or T4 elevation suppresses TSH in the serum, whereas their fall increase the level of TSH in serum, an early and specific indicator of primary hypothyroidism.
The presence of autoantibodies to thyroid antigens is an indication of autoimmune thyroiditis. These autoantibodies target the thyroid glands and its hormone products T3, T4 and TSH leading to hormonal dysfunction. Detection of such autoantibodies in an indication of chronic autoimmune thyroiditis, hence a marker for the differential diagnosis of hypothyroidism and the subclinical or latent type.
|Title||SELco® TSH rapid|
|Description||Radioimmunoassay for the quantitative determination of Thyrotropin (TSH) in human serum|
|Format||Coated tube technology|
|Total incubation time||30 minutes|
|Sample volume||100 µL|
|No. of determinations||100 (91 x 1) + 7 x Calibrators + 2 x Controls|